People change.  And when they do, their brains change too.

The MyConnectome project has characterized how the brain of one person changes over the course of more than one year.  It is almost certainly the most ambitious study of a single living person’s brain ever attempted. The data will provide new insights into the dynamics of brain activity and their relationship to bodily metabolism and psychological function.  The project is also openly sharing a large amount of biological data for future reuse.

See media coverage of the project at the Dana FoundationPriceonomics, MIT Tech Review, Austin Monthly, and NPR.

The data from this study have already resulted in a number of academic papers:

Laumann T, Gordon E, Adeyemo B, Snyder AZ, Joo SJ, Chen MY, Mumford JA, Poldrack RA, Petersen SE (2015). Functional network and areal organization of a densely-sampled individual human brain. Neuron, 87, 657-70.

Qin Y, Yao J, Wu DC, Nottingham RM, Mohr S, Hunicke-Smith S, Lambowitz AM (2015).  High-throughput sequencing of human plasma RNA by using thermostable group II intron reverse transcriptase
RNA,  22: 111-128.  

Betzel RF, Satterthwaite TD, Gold JI, Bassett DS (2016).  A positive mood, a flexible brain.  arXiv:1601.07881 

Shine JM, Koyejo O, Poldrack RA (2016).  Temporal meta-states are associated with differential patterns of dynamic connectivity, network topology and attention.  arXiv:1601.05065 

Power JD (2016). A simple but useful way to assess fMRI scan qualities. Neuroimage.